MEDICAL RESEARCH CENTRE-KASTURBA HEALTH SOCIETY

AWARD-1

Hiteshi Dhami-Shah was invited to attend the “International Conference on Obesity and Chronic Diseases 2016” held in Las Vegas- USA from 25th to 27th July.  She participated in the poster presentation and was awarded first prize for her poster titled “Simulation in an in vitro NAFLD model showed inhibition of lipid accumulation and lipotoxicity by Picroside II”. Her work is in the area of obesity - linked non-alcoholic fatty liver disease (NAFLD). NAFLD is prevalent in our country as co-morbidity with obesity and type 2 diabetes mellitus. If not diagnosed/treated early, it can progress to severe form like cirrhosis of liver and at times even progress to liver cancer. Hiteshi had simulated and standardized an in-vitro model of fatty infiltration in hepatocytes (HepG2 cells) with experimental induction of lipotoxicity so as to have a rapid drug-screening assay. In the course of her work she has identified through the platform of Reverse Pharmacology Picroside II, lead molecule against NAFLD in her in-vitro assay.




Hiteshi is a PhD student at the SNDT University Mumbai, working under the guidance of Dr. Shobha Udipi and Dr. Ashok Vaidya. She is a PhD scholar at Medical Research Centre-Kasturba Health Society- Mumbai

Hiteshi receiving the best poster award from Dr. Reza Hakkak of University   of Arkansas for Medical Sciences- USA